Monthly Archives: October 2013

Bottlenecks and Slow Steps – again

I’ve written a few articles on this blog about the irrationality of bottlenecks and slow steps in metabolism, hoping that one day my fellow scientists will feel the same. Sadly it is not true and maybe I should write more … Continue reading

Posted in Enzyme Kinetics, Metabolic Control Analysis, Modeling, Pathways | Leave a comment

Whole Cell Models

We’ve seen in the last couple of years increased interest in building whole cell models, that is computer models that attempt to simulate a whole organism. The most recent attempt was by Karr et al, published in Cell, 2012, 150(2), … Continue reading

Posted in General Science Interest, Modeling, Molecular Biology, Pathways, Software | Leave a comment