Category Archives: Enzyme Kinetics

It’s Christmas!

It’s Christmas, term is winding down at the University, the students are going home and than means spare time to do something other than official work. Here is a small Windows App I wrote that simulates a simple enzyme mechanism. … Continue reading

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Modeling Webinar Hosted by Rosa

Modeling Webinar I will be presenting a Webinar hosted by Rosa to be held on Tuesday 26th of July at 12:00 to 1:00 pm EDT on Standards and Software in Biomedical Systems Modeling. Register here if you wish to attend … Continue reading

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SBML Parts Decomposition Tool

Biochemical Pathway Component Finder Ever wanted to extract a particular enzyme or reaction from a computational model? Perhaps not, but those of you who have, there is now a tool available to do that very task. Maxwell Neal from University … Continue reading

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Systems Thinking in Systems Biology: Part 2

In the last post I posed the question, what would happen to a metabolic pathway if we added an inhibitory drug to the middle enzyme in a linear sequence of steps? Here is the answer. Take a sequence of enzymes … Continue reading

Posted in Enzyme Kinetics, Molecular Biology, Pathways, Systems Theory | 1 Comment

Systems Thinking in Systems Biology: Part 1

Let’s say we inhibit an enzyme in a metabolic pathway by perhaps reducing the expression of the gene that makes the enzyme or more easily by adding a drug that inhibits the enzyme.What do you think will happen? When I … Continue reading

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Proportional and Relative Changes

There is an excellent description of the difference between logarithmic and linear scales in the book “Mathematical Analysis for Economists” by R Allen which I describe here. Consider the following two sequences of numbers: 100,  150,  200,  250,    300,     100,  … Continue reading

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New Text Book: Enzyme Kinetics for Systems Biology

I have finally got to the point where I can publish my text book: Enzyme Kinetics for Systems Biology This text is geared towards those who need a reference or classroom text book that describes the various rate laws one … Continue reading

Posted in Enzyme Kinetics, Publishing | Tagged | 3 Comments