Category Archives: General Science Interest

New 17 million-digit prime number

Recent news announced the discovery of a new Mersenne prime. What was interest was the response I saw on some of the boards that where reporting this news, for example: “but can someone explain how digging up mersene prime numbers … Continue reading

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Building an Analog Integrator

Something I’ve been wanting to do for a while was is to build a simple analog integrator. Here is my first attempt. I bread-boarded the circuit first to get it working then made it more permanent and stable by soldering … Continue reading

Posted in Electronics, General Science Interest, Systems Theory | Leave a comment

Self-Publishing: A Personal Experience

As some of you may know, a year ago I published my book ‘Enzyme Kinetics for Systems Biology’ and I am about to release the second edition. Next year the hope is to publish another title. Self-publishing my own book … Continue reading

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LaTeX and Chemistry

I recent had the need to draw some chemical equation in a LaTeX document. In the past I’ve used ChemDraw and loaded the image into my document as a png file. Last time I used ChemDraw was on my old … Continue reading

Posted in Chemistry, General Science Interest, LaTeX, Programming | 2 Comments

Electronic Gene Circuit

The figure below shows a single unit from the Microryza gene network circuit project. The circuit models a transcription factor that acts as a repressor. The output from the circuit is the level of protein which can be fed into … Continue reading

Posted in Electronics, Enzyme Kinetics, General Science Interest, Modeling, Molecular Biology, Synthetic Biology, Systems Theory | Leave a comment

A mini-supercomputer for the rest of us

I recently contributed to the kickstarter project, Parallela which I would like to selfishly mention here. This is an interesting project that wants to develop highly cost effective small parallel machines. For example their smallest multi-process machine will cost $99 … Continue reading

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Misconceptions in Metabolism II

A week ago I wrote about some misconceptions in metabolism that arose from a trip to a systems biology workshop in Holland. This week I discovered that Nature is perpetrating similar misconceptions in their News and Views section. I came … Continue reading

Posted in Enzyme Kinetics, General Science Interest, Metabolic Control Analysis, Molecular Biology, Pathways, Systems Theory | Leave a comment

Misconceptions in Metabolism

I’m currently at the ISGSB meeting (International Study group for Systems Biology – formally BTK) in Holland. This is a group that values both theoretical analysis and experimentation in biochemical network analysis. Its an interesting group of people that I have literally … Continue reading

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Ludicrous as it may sound

I was reminded the other day of an interesting quote from a 2000 FEBS paper which starts with: “How highly would one rate an economic analysis of a factory that ignored the consumer demand for its products? Ludicrous as it … Continue reading

Posted in General Science Interest, Metabolic Control Analysis, Modeling, Pathways, Systems Theory | Leave a comment

Why are Systems Biologists so bad at Computer Modeling?

The title of this blog is meant to be a little brazen and eye catching but I decided to write it after having been on a variety of government grant panels over the years where I am always shocked at the … Continue reading

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