Category Archives: Molecular Biology

Electronic Gene Circuit

The figure below shows a single unit from the Microryza gene network circuit project. The circuit models a transcription factor that acts as a repressor. The output from the circuit is the level of protein which can be fed into … Continue reading

Posted in Electronics, Enzyme Kinetics, General Science Interest, Modeling, Molecular Biology, Synthetic Biology, Systems Theory | Leave a comment

Misconceptions in Metabolism II

A week ago I wrote about some misconceptions in metabolism that arose from a trip to a systems biology workshop in Holland. This week I discovered that Nature is perpetrating similar misconceptions in their News and Views section. I came … Continue reading

Posted in Enzyme Kinetics, General Science Interest, Metabolic Control Analysis, Molecular Biology, Pathways, Systems Theory | Leave a comment

NCI Partners with the DREAM Project

Two acronyms in one title, translated the title says: The National Cancer Institute Partners with the Dialogue for Reverse Engineering Assessments and Methods. Perhaps not much help but actually this is a great idea. The National Caner Institute is partnering with … Continue reading

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Did Venter Create Life?

Perhaps a bit late but the topic of whether Venter actually created new life came up again in a recent workshop I was at, the conclusion: No So what did he do? By analogy what he did was akin to … Continue reading

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Teaching Teachers about Synthetic Biology

Natalie Kuldell is an accomplished instructor at MIT where she teaches biological engineering, including synthetic biology and design. She has also recently set up the BioBuilder web site which is geared towards providing educational and other resources for the synthetic … Continue reading

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Tenure Track Position – Synthetic Biology

Tenure Track Position in Synthetic Biology at UW 21th February 2012 The University of Washington Department of Bioengineering Invites Applications for Tenure Track Position in Synthetic Biology The Department of Bioengineering at the University of Washington (UW) invites applications for … Continue reading

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Scientists Patent the Scientific Method

There has been a lot of talk in the news about the patent office awarding obvious or frivolous patents. I recently came across this one awarded to Palsson, Covert and Herrgard. I only read the abstract which is given here: “The present invention provides … Continue reading

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Modeling Course at Indiana University

Not that kind of modeling, but the kind that involves building computational models of biochemical networks and multicellular systems. James Glazier, the Director of the Biocomplexity Institute at Indiana University is the lead organizer behind a series of workshops that … Continue reading

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Standards in Synthetic Biology: Part 1

Standards What are standards and why should we bother developing them? I suspect to many people including my fellow scientists and perhaps even some engineers, that standards are nether a rewarding nor worthwhile endeavor. Standards however are the invisible hand … Continue reading

Posted in General Science Interest, Molecular Biology, Pathways, SBML, Synthetic Biology | 2 Comments

MAPK: Feedback Amplifier, Part I

A recent paper by Sturm et al., report results that support the hypothesis that the MAPK cascade acts as a negative feedback amplifier. The systems biology literature is full of reviews and articles about oscillators and bistable systems and very little else other than … Continue reading

Posted in General Science Interest, Molecular Biology, Pathways, Systems Theory | 2 Comments